Valvular Heart Disease 4th : A Companion to Braunwald’s Heart Disease, 2014

The fourth edition of Valvular Heart Disease: A Companion to Braunwald’s Heart Disease follows the format of the previous edition. The  initial  section  focuses  on  basic  principles,  epidemiology, mechanisms of disease, and diagnostic methods. This is followed by  a  second  section  covering  aortic  valve  disease  and  a  third covering mitral valve disease. The final section discusses diverse topics  including  intraoperative  echocardiography,  right-sided valve disease, endocarditis, prosthetic valves, and management of valvular heart disease during pregnancy. Among the many enhancements found in the fourth edition are the  four  new  chapters  that  open  the  basic  principles section. These include a chapter on the global epidemiology of valvular heart disease by Drs. John Chambers and Ben Bridgewater, two entirely  new  chapters  on  the  molecular  mechanisms  of  calcific valve disease by Dr. Jordan Miller, and a chapter on the clinical, cellular, and genetic risk factors for calcific valve disease by Drs. Kevin O’Brien and David Owens. Drs. Roberto Lang, Wendy Tsang, and Benjamin Freed have together written a superb new chapter on the three-dimensional anatomy of the mitral and aortic valves; this chapter includes insights gleaned from their experience with the three-dimensional imaging of these structures.

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